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Prof. Jingjing Zhang
MD, PhD

Assistant Professor (Tenure Track), Department of Diagnostic Radiology

Lead: Theranostics Center of Excellence (TCE)

Principal Investigator, Clinical Imaging Research Centre, Centre for Translational Medicine

Principal Investigator, Nanomedicine Translational Research Programme

Yong Loo Lin School of Medicine

National University of Singapore (NUS), Singapore

Email: j.zhang@nus.edu.sg

Webpages: http://www.jjzlab.com/;  https://medicine.nus.edu.sg/meddnr/staff.html

RESEARCH OVERVIEW

Dr. Zhang contributed to the fields of molecular imaging and theranosts for over 15 years. Since joining NUS in Oct 2021, I have established an impactful and productive research program, established and led the Theranostics Center of Excellence (TCE) at NUS. Her research focuses on the following areas: translation of theranostics for cancer diagnosis and therapy; development of small molecules, peptides, proteins and antibodies for molecular imaging and therapy; translational nanomedicine and multifunctional nanoplatforms; advancing multimodality molecular and functional imaging platforms, including optical, X-ray, ultrasound, photoacoustic, PET/MRI, PET/CT, and SPECT/CT; radiomics and AI-aided precision medicine. She has consistently produced impactful research and published in top journals. Collectively, she has published 102 articles, and she has published 58 articles since she joined NUS, among them, she is the first/corresponding/last author on 41. Her first-authored and last-authored review papers were published in prestigious journals, such as Nature Reviews Bioengineering, and Accounts of Chemical Research (cover).   As an Assistant Professor in NUS, She has published 41 articles as corresponding author and 19 articles as the last and corresponding senior author. Her research articles were published in top journals, including: Journal of Nuclear Medicine (Ranked 1st in Nuclear Medicine, Radiotherapy, and Molecular Imaging by Google Scholar); Lancet Oncology; Nature Reviews Bioengineering; Accounts of Chemical Research; Theranostics; ACS Nano; European Journal of Nuclear Medicine and Molecular Imaging; Signal Transduction and Targeted Therapy; Aggregate; Clinical Cancer Research; Advanced Science

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三鐵血顏色

PUBLICATIONS

Total Publications: > 100

H-index: 30 (SCOPUS)

Academic Books

  1. Book Title: Cancer Theranostics (2nd edition)

    • Publisher: Elsevier

    • Publication Year: 2025

    • Editors: Jingjing Zhang, Stephen Wong, Xiaoyuan Chen

  2. Book Chapters:

    1. Clinical Translation and Regulations of Theranostics
      Authors: Jingjing Zhang*, Tianzhi Zhao, Vivianne Jakobsson, Xiaoyuan Chen*

    2. Cancer Theranostics: An Introduction
      Authors: Xiaoyuan Chen*, Jingjing Zhang*

    3. Atlas of PSMA-Targeted Theranostics Authors: Richard P. Baum, Vivianne Jakobsson, Jingjing Zhang 

    4. Treatment of Differentiated Thyroid Cancer in Children and Adolescents

Authors: Fei Yu, Jingjing Zhang

MEMBERSHIPS IN MAJOR PROFESSIONAL SOCIETIES

Regional Member of the ICPO Centers and Patient Access Steering Committee, International Centers for Precision Oncology (ICPO) Academy, Germany;

Member of the Society of Nuclear Medicine and Molecular Imaging (SNMMI, USA), Member of the European Association of Nuclear Medicine (EANM), Member of Nuclear Medicine Society (Singapore), Member of World Association of Radionuclide and Molecular Therapy (WARMTH), Member of International Centers for Precision Oncology (ICPO).

EMPLOYMENT HISTORY

1.09/2021-Present Assistant Professor (Tenure Track) Department of Diagnostic Radiology, Yong Loo Lin School of Medicine, National University of Singapore (NUS), Singapore 119074, Singapore 2.06/2022-Present Principal Investigator Internal joint appointment to the Clinical Imaging Research Centre, Centre for Translational Medicine, National University of Singapore (NUS), Singapore 117599, Singapore 3.06/2022-Present Principal Investigator Internal joint appointment to the Nanomedicine Translational Research Programme, National University of Singapore (NUS), Singapore 117597, Singapore 4.09/2022-08/2023 Dean of Research International academic appointment, International Centers for Precision Oncology (ICPO) Academy, Wiesbaden, Germany 5.2018-2020 Nuclear Medicine Clinical & Research Fellow THERANOSTICS Center for Molecular Radiotherapy and Precision Oncology, Zentralklinik Bad Berka, Bad Berka 99437, Germany 6.2015-2017 Nuclear Medicine Physician Chinese Academy of Medical Sciences & Peking Union Medical College (CAMS & PUMC), Peking Union Medical College Hospital (PUMCH), Beijing 100730, PR China

EDITORIAL AND JOURNAL REVIEW ACTIVITIES

Editorial Board 1.Theranostics (Impact Factor = 12.4) 2.Clinical Nuclear Medicine (Impact Factor: 10) Referee 1.Journal of Nuclear Medicine (JNM) 2.European Journal of Nuclear Medicine and Molecular Imaging 3.Theranostics 4.Clinical Nuclear Medicine (CNM) 5.Molecular Pharmaceutics (ACS Publications) 6.Bioconjugate Chemistry 7.Nano Today 8.iScience  9.EJNMMI Research  10.Swiss National Science Foundation - scientific evaluation Guest Editor Roles 1.Theranostics: Special Issue on "Molecular Imaging and Theranostics" (Impact Factor: 12.4) 2.iScience (Cell Press): Special Issue on "Molecules and Materials for Theranostic Applications" (Impact Factor: 5.8)

EDUCATION / PROFESSIONAL EXPERIENCE

09/2021-Present Assistant Professor (Tenure Track) Department of Diagnostic Radiology, Yong Loo Lin School of Medicine, National University of Singapore (NUS), Singapore 119074, Singapore 06/2022-Present Principal Investigator Internal joint appointment to the Clinical Imaging Research Centre, Centre for Translational Medicine, National University of Singapore (NUS), Singapore 117599, Singapore 06/2022-Present Principal Investigator Internal joint appointment to the Nanomedicine Translational Research Programme, National University of Singapore (NUS), Singapore 117597, Singapore 09/2022-08/2023 Dean of Research International academic appointment, International Centers for Precision Oncology (ICPO) Academy, Wiesbaden, Germany 2018-2020 Nuclear Medicine Clinical & Research Fellow THERANOSTICS Center for Molecular Radiotherapy and Precision Oncology, Zentralklinik Bad Berka, Bad Berka 99437, Germany 2015-2017 Nuclear Medicine Physician Chinese Academy of Medical Sciences & Peking Union Medical College (CAMS & PUMC), Peking Union Medical College Hospital (PUMCH), Beijing 100730, PR China

FUNDING SUPPORT as Lead PI

1.Singapore NMRC CS-IRG Grant, Project Title “Radiolabeled Albumin-binding Somatostatin Analog 177Lu-DOTA-EB-TATE for Peptide Receptor Radionuclide Therapy of Recurrent or Metastatic Nasopharyngeal Carcinoma”. CIRG23jul-0019 (2024 - 2027). SGD $1,950,000.00. Principal Investigator. (Funded) 2.Singapore NMRC CS-OFYIRG Grant, Project Title “Novel Gastrin-releasing peptide receptor (GRPR) and Integrin αVβ3 Dual-targeting Probes for Radiotheranostics of Prostate Cancer”. MOH-001334-00. CNIG22jul-0007. (September 2023 - August 2026). SGD $325,000.00. Principal Investigator. (Funded)  3.Tsinghua-NUS Joint Research Initiative Fund. Project Title “Controlled green synthesis of novel radioactive microspheres and their antitumor study by transcatheter arterial radiotherapy emboliation. (1/7/2024- 30/6/2026). SGD $40,000.00. Principal Investigator. (Funded)  4.The Academic Health Programme (AHP) Fund 2024. Project Title “FAP-Targeted Nanoplatform for Sensitized Radionuclide Therapy and Immunotherapy of Deep-Seated Cancers”. SGD $50,000.00. Principal Investigator. (Funded)  5.External funding from LNC Pharma. Project Title “Phase I, Open-Label Study of the Safety and Dosimetry of a 4-Dose Regimen of Escalating Doses of 177Lu-LNC1004 Injection in Adult Patients with Advanced Fibroblast Activation Protein (FAP)-Positive Solid Tumors”. SGD $76778.42. (Funded) 6.International (Europe) ICPO Grant. Project Title “FAP Theranostics - Cancer-Associated Fibroblasts (CAFs)-Targeted Imaging and Therapy and Combination with Immunotherapy or Chemotherapy (including also other radioligands)”. (December 2022 - November 2023). Euro €50,000.00. Principal Investigator. (Funded) 7.National University of Singapore (NUS) Start-up Fund, Title “Radionuclide Theranostics” (Jan 2022-Jan 2025). Goal: To develop various forms of radionuclide Theranostics platforms for cancer diagnosis and therapy. SGD $1,000,000.00. Principal Investigator. (Funded) 8.NMRC CS-IRG NIG Grant, Project Title “68Ga-FAPI-46 PET/CT of Peritoneal Metastases in Patients with Gastric Cancer”. CNIG22jul-0007. (March 2023 - February 2025). SGD $260,000.00. Principal Investigator. (Funded) 9.Singapore MOE Tier 1 Grant, Project Title “Novel Dimeric Long-Acting Fibroblast Activation Protein Inhibitors for Radioligand Imaging and Therapy of Cancer” (March 2023-February 2026). NUHSRO/ 2022/093/T1/Seed-Sep/06. SGD $250,000.00. Principal Investigator. (Funded) 10.Innovation Fund Project of Chinese Academy of Medical Sciences & Peking Union Medical College, Project Title “Clinical Translational Research on Detection of the Tumor causing Osteomalacia via 68Ga-DOTA-TATE PET/CT” (No. 2012-1002-016). Principal Investigator. (Completed) 11.Youth Fund and the Fundamental Research Funds for the Central Universities, Project Title “Clinical Translation of 68Ga-BBN-RGD PET for GRPR and Integrin αvβ3 Imaging in Patients with Breast Cancer” (No. 2017320003). Principal Investigator. (Completed) 12.National Natural Science Foundation of China projects, Project Title “Radioligand Precision System Construction in Prostate Cancer based on dual GRPR and Integrin αvβ3 targeting Thranostics Agents Development and Optimization” (No. 81701742). Principal Investigator. (Completed) (2017)

HONORS AND AWARDS

1.National University of Singapore, Yong Loo Lin School of Medicine, “Young Researcher of the Year Award for 2024”. NUS. Singapore 2023-2024 2.The SNMMI 2023 International Best Abstract Award (Singapore), SNMMI, USA  3.Thomas O’Dorisio Young Investigator Award in NETs in 2022 (only 1 awardee every two years world-wide), Germany 4.Travel Awards of Society of Nuclear Medicine and Molecular Imaging (SNMMI) Annual Meeting (SNMMI 2023) 5.The SNMMI 2022 International Best Abstract Award for Singapore in 2022. Society of Nuclear Medicine and Molecular Imaging (SNMMI), USA 6.Identified as one of thirty early career professionals who stand out as “Ones to Watch” in 2019. Society of Nuclear Medicine and Molecular Imaging (SNMMI), USA 7.Alavi-Mandell Award for the publication entitled, “Clinical translation of a dual integrin αvβ3 and GRPR targeting PET radiotracer 68Ga-NOTA-BBN-RGD” in JNM. SNMMI 2018, Philadelphia, Pennsylvania, USA 8.Majd-Gilday Investigator Award. Society of Nuclear Medicine and Molecular Imaging (SNMMI). 2017. 06. Denver, Colorado, USA 9.Young Professionals Committee (YPC) Prize. Society of Nuclear Medicine and Molecular Imaging (SNMMI). 2017. 06. Denver, Colorado, USA 10.Young Scientist Award (YSA). Chinese-American Society of Nuclear Medicine and Molecular Imaging (CASNMMI). 2017. 06. Denver, Colorado, USA 11.Alavi-Mandell Award for the publication entitled, “68Ga-NOTA-Aca-BBN (7-14) PET/CT in Healthy Volunteers and Glioma Patients” in JNM. SNMMI 2017. Denver, Colorado, USA 12.Alavi-Mandell Award for the publication entitled, “Clinical Translation of an Albumin-Binding PET Radiotracer 68Ga-NEB” in JNM. SNMMI 2016. San Diego, California, USA 13.Young Scientist Award (YSA). Chinese American Society of Nuclear Medicine and Molecular Imaging (CASNMMI). 2015. 06. Baltimore, Maryland, USA 14.Women in Molecular Imaging Scholar Award. World Molecular Imaging Congress (WMIC). 2015. 09. Honolulu, Hawaii, USA 15.Young Scientist Award (YSA). Chinese American Society of Nuclear Medicine and Molecular Imaging (CASNMMI). 2014. 06. St. Louis, MO, USA 16.Travel Awards of Society of Nuclear Medicine and Molecular Imaging (SNMMI) Annual Meeting (SNMMI 2014, SNMMI 2015) 17.Travel Awards of THERANOSTICS World Congress (2018) 18.Travel Awards of World Molecular Imaging Congress (WMIC 2012, WMIC 2014, WMIC 2015)

Contact Us

Questions?
Contact Me Any Time

Yong Loo Lin School of Medicine National University of Singapore

Department of Diagnostic Radiology

National University Hospital, 

Main Building, Lobby F, Level 4

#04-398, DDI Library

5 Lower Kent Ridge Road

Singapore 119074

j.zhang@nus.edu.sg

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